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A resorbable collagen plug venous closure device got patients on their feet faster than did manual compression alone after a catheter-based electrophysiology procedure, according to the AMBULATE trial published online in JACC: Clinical Electrophysiology.
Vascular closure with the Vascade MVP device led to faster recovery after cardiac ablation, and with less pain medication use, than seen with randomization to manual compression, with time to ambulation (when patient stood and walked 20 feet): 2.8 vs 6.1 hours; total post-procedure time (from removal of the last device for the index procedure to up and walking): 3.1 vs 6.8 hours; time to hemostasis: 6.1 vs 13.7 min; time to eligibility for hospital discharge based on the assessment of the access site: 3.1 vs 6.5 hours; pain medication usage: 24% vs 49%; and opioid use: 15% vs 36%.