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Medical Voice 27th January 2020

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Dr KK Aggarwal    27 January 2020

Jumping genes provides stability to DNA folding patterns

These genes which are also called transposable elements are well-known for increasing genetic diversity over the long course of evolution.

Washington D.C. : A new research has identified that jumping genes - bits of DNA that can move from one spot in the genome to another - play a major role in stabilising the 3D folding patterns of the DNA molecule inside the cells nucleus.

These genes which are also called transposable elements are well-known for increasing genetic diversity over the long course of evolution....read more

Health Sutras By Dr K K Aggarwal

To revive a cardiac arrest victim, compress the center of the chest of the victim within 10 minutes of death (earlier the better) atleast for the next 10 minutes (longer the better), with a speed of atleast 10x10=100 per minute.

Healthcare News Monitor

 

Alembic Pharma gets final USFDA nod for Fenofibrate tablets

ET Healthworld - PTI

Alembic Pharmaceuticals on Thursday said it has received final nod from the US health regulator for fenofibrate tablets, which reduces cholesterol and triglycerides in blood. "Alembic Pharmaceuticals Limited (Alembic)...has received final approval from the US Food & Drug Administration (USFDA) for its Abbreviated New Drug Application (ANDA) Fenofibrate Tablets USP, 54 mg and 160 mg. "The approved ANDA is therapeutically equivalent to the reference listed drug product (RLD) Tricor Tablets, 54 mg and 160 mg, of AbbVie Inc (AbbVie)," the drug firm said in a BSE filing. Fenofibrate tablets have an estimated market size of USD 100 million for twelve months ending September 2019, according to IQVIA. "Fenofibrate tablets are indicated as an adjunct to diet to reduce elevated LDL-C, Total-C, TG and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidaemia and for treatment of adult patients with severe hypertriglyceridemia," it said. Alembic has a cumulative total of 113 ANDA approvals -- 100 final approvals and 13 tentative approvals -- from the USFDA.

Srepta shares fall 4% after FDA documents show safety concern about drug

ET Healthworld – Carl ODonnell

Shares of Sarepta Therapeutics Inc were down around 4% Wednesday after the U.S. Food and Drug Administration revealed documents detailing concerns it had about the safety and efficacy of one of the companys recently approved Duchenne muscular dystrophy (DMD) drugs. The drug, Vyondys 53, also known as golodirsen, was originally rejected by the FDA last year before the agency reversed that decision in December and approved it. It was the second controversial drug approval for Sarepta. The company saw its first drug, Exondys 51, which also treats DMD, approved in 2016 despite concerns raised by experts about its effectiveness.

Bihar Doctor Charred to Death in Bareilly College Hostel, Room Heater Suspected to Have Caused Fire

News18- Qazi Faraz Ahmad

A young doctor from Bihar, who had recently completed her MBBS, was burnt to death in her hostel room early on Friday. The college authorities suspect that the room heater may have sparked the fire. Dr Sukirti Sharma was interning with SRMS Institute of Medical Sciences in the Bhojipura area of Bareilly, where the incident occurred. According to information, the hostel authorities saw smoke coming out of the single-bed hostel room of Sukirti Sharma, following which the fire department was called up. However, by the time, firefighters doused the blaze, the fire had engulfed the entire building and charred body of the doctor was found in room number 302. The family members of the deceased have been informed but the actual reason behind the fire and death of Sharma is yet to be ascertained. Initial theories suggest that the room heater had caused the fire. Speaking to reporters, SRMS Medical College principal Dr SB Gupta said, "There was a room heater in the hostel room of Sukirti, which might had led to the fire. When smoke was spotted from the room, college authorities were informed, who in turn informed the fire brigade along with police. By the time the fire was doused, the doctor had died." As soon as the news of the incident spread, senior police officials including SP (Rural) Dr Sansar Singh reached the spot. "The family members of the girl have been informed and forensic team has reached the spot to investigate the matter. The college authorities have been speaking about the fire from room heater. The body has been charred and is being sent for the post morterm."

Kerala: Doctor forced to resign, accused of being genocidal and ‘religious fanatic’ for seeking deportation of illegal immigrants

OP India

The passage of the Citizenship Amendment Act has exposed the deep faultlines within Indian society. The anti-Hindu bigotry and Islamic Supremacy that was evident in all the anti-CAA protests have opened a can of worms. Now, it appears that the anti-CAA crowd has progressed from chanting hateful slogans to targeting people in vulnerable locations for their support towards the CAA. Vyas Vishwanathan, a Doctor by profession, was doxxed, accused of being genocidal without any proper evidence and ultimately forced to resign from the hospital he worked in at Palakkad, Kerala. On the 20th of January, he was given 24 hours within which to submit his resignation and vacate his room. And Dr Vishwanathan had to endure the entire ordeal only because he supported the CAA on social media and voiced his support for measures to throw out illegal immigrants out of the country. It all began on the 19th of January when a Twitter handle @yehlog published personal details of Dr Vishwanathan online with the primary intention of damaging his reputation and his career prospects. She accused him of being a ‘religious fanatic’ who wants to ‘kick out Muslims’ from the country.

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