A recent article published in the Journal of Biological Regulators and Homeostatic Agents discussed that osteogenesis can be stimulated through biophysical therapy, which can be performed using inductive, capacitive, mechanic or implanted devices. The authors elaborated that the mechanism of action of physical stimuli is at a membrane level, where the activation of calcium channels determines the enhancement of cell proliferation and the production of growth factors. Biophysical therapy should be performed using devices and modalities described in literature.

This article further stated that the biophysical stimulation of osteogenesis is effective in the enhancement of the biology of fracture healing in the presence of a correct orthopedic treatment—in terms of good alignment and stabilization at the fracture site.

Moreover, the choice of the method must depend on the segment of bone that has to be treated, the type of fracture and whether it is feasible to apply the device on the skin. The presence of internal or external fixation devices is not a contraindication.

Source: Journal of Biological Regulators and Homeostatic Agents. 2020 Jan-Feb;34(1 Suppl. 2):19-24.