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A nationwide US observational study has suggested that ACE inhibitors may be protective against severe illness in older people with COVID-19, propelling a randomized clinical trial to test the strategy.
Furthermore, a new meta-analysis of all the available data on the use of ACE inhibitors and angiotensin-receptor blockers (ARBs) in COVID-19–infected patients has revealed that these drugs are not associated with more severe disease and do not heighten the susceptibility to infection.
The observational study, published on the MedRxiv preprint server, noted that the use of ACE inhibitors was tied to an almost 40% lower risk for COVID-19 hospitalization for older people enrolled in Medicare Advantage plans… (Medscape)