CMAAO Coronavirus Facts and Myth Buster: ChAdOx1 nCoV-19 and transverse myelitis

With input from Dr Monica Vasudev1.AstraZeneca had voluntarily halted a randomized clinical trial of its coronavirus vaccine after a volunteer developed transverse myelitis (NY Times).Phase 1/2, single-blind, randomized controlled trial at five trial sites in the UK of a chimpanzee adenovirus-vectored vaccine (ChAdOx1 nCoV-19) expressing the SARS-CoV-2 spike protein compared with a meningococcal conjugate vaccine (MenACWY) as control.3.We presume that the team has confirmed that the case was not in the control arm. ....read more

World COVID Meter 12th September: Acute manageable immunogenic thrombogenic inflammatory viral disease pandemic

Cases: 1M April 2, 2M April 15, 3M April 27, 4M May 8, 5M May 20, 6M May 30, 7M June 7, 8M June 15, 9M June 22, 10M June 29th, 11M July 4, 12M July 8, 13M July 13, 14M July 17, 15M July 23, 16M July 25, 17M July 29, 18M August 1, 19M August 6, 20M August 10, 21M August 16, 22M August 19, 23M August 21, 24M August 27, 25M August 30, 26M September 3, 27M September 7, 28M September 10 Ground Zero: Wuhan - in live animal market or cafeteria for animal pathogens: 10th January; Total cases are based on RT PCR, 67% sensitivity Coronavirus Cases: 28,647,471,Deaths: 919,512,Recovered: 20,570,938 ,ACTIVE CASES 7,157,021 ....read more

Think differently in mythology

Lord Ganesha’s elephant head depicts that one should use his/her wisdom before taking any decision.Vishnu’s first incarnation, fish, symbolizes need to learn to swim in the opposite direction.Brahma’s five heads mean to use all five senses before taking any decision. ....read more

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Self Protection from Respiratory Illnesses

Healthcare News Monitor

Granules India arm gets USFDA gesture for ADHD treatment drug

Microbioz India

New Delhi, Sep 11 (PTI) Medication firm Granules India Friday said its subsidiary has received marketing approval from the US health regulator for Dexmethylphenidate HCl extended-release capsules, used for the treatment of attention-deficit hyperactivity disorder (ADHD). The approved product is bioequivalent to the reference listed drug Focalin XR of Novartis AG. In a BSE filing, Granules said its US subsidiary has received marketing approval from the US Food and Drug Administration (USFDA) for Dexmethylphenidate HCl extended-release capsules. The company said the recently approved drug will be manufactured at the Granules” manufacturing facility in Chantilly, Virginia.

PNB Vesper to conduct Phase-II human trial of a new COVID-19 drug

Business Today

Pharmaceutical drug research company PNB Vesper Life Science has received approval from the Drug Controller General of India (DCGI) to conduct the Phase 2b clinical trial of its candidate drug PNB-001 (GPP-Baladol), a novel chemical entity that was being researched to treat small cell lung cancer, for treating COVID-19 patients. The trials on 40 COVID-19 positive patients at BMJ Medical College, Pune will be completed in 60 days. These are moderate cases of COVID-19 and patients are on the oxygen support. The effect of PNB 001 will be compared with Dexamethasone, a popular steroid with anti-inflammatory properties now used in COVID-19 treatment. A larger study of approximately 350 COVID-19 patients will be enrolled across the country in six medical Colleges in the Phase 3 clinical trials, after reviewing the phase 2 clinical trial results and further regulatory permissions, said PN Balaram, CEO of PNB Vesper.

US hospitals turn down remdesivir, limit use to sickest coronavirus patients

India Today

US hospitals have turned down about a third of their allocated supplies of the Covid-19 drug remdesivir since July as need for the costly antiviral wanes, the Department of Health and Human Services (HHS) confirmed on Friday. Some hospitals said they are still buying the Gilead Sciences GILD.O medicine to build inventory in case the pandemic accelerates over the winter. But they said current supplies are adequate, in part because they are limiting use to severely ill patients. The Food and Drug Administration has allowed more liberal remdesivir use, but 6 out of 8 major hospital systems contacted by Reuters said they were not using it for moderate cases.

Civil Hospital gets contactless sink for visitors to wash hands

tribuneindia

A foot-operated contactless sink for washing hands was installed at the Civil Hospital on Thursday by the philanthropy wing of Hyatt Regency, Amritsar. District Civil Surgeon Dr Navdeep Singh, who was present on the occasion, said such voluntary community welfare efforts must be appreciated to encourage more people to help the needy during the pandemic. The Civil Hospital gets maximum rush of patients during the pandemic. “We believe in communal harmony and that’s the message we want to send across people. Our community initiative Shanti Sewa was launched during the pandemic and we are on the frontline delivering groceries and other items to the vulnerable members within the community during this pandemic. Besides food, other essential commodities such as soaps, sanitisers and fresh linen were also being provided by the organisation. April 2020 was commenced by distributing more than 350 freshly cooked food packets to BPL families in the nearby areas and till date, the organisation has distributed free food ingredients, soaps, sanitisers, face masks and gloves to more than 5,000 persons,” said Kamaljit Singh, GM, Hyatt Regency.