Active and passive cigarette smoke exposure was found to raise the risk of colorectal neoplasia in patients with inflammatory bowel disease (IBD), suggested a cohort study from the Netherlands. In corporating this risk factor would improve current risk stratification for surveillance strategies for colorectal neoplasia.

Researchers noted that by IBD type, past smoking heightened the risk for colorectal neoplasia in ulcerative colitis (UC), with a hazard ratio (HR) of 1.73 (95% CI 1.05-2.85), while passive smoke exposure had no impact. For those with Crohns disease (CD), both active and passive smoke exposure significantly increased the risk, with HR of 2.20 (95% CI 1.02-4.76) and 1.87 (1.09-3.20), respectively. The study is published online in Clinical Gastroenterology and Hepatology… (Medpage Today)