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Daily Dengue Severity Score to Assess Severe Manifestations

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A recent study published in Pediatr Infect, stated that daily dengue severity score of ≥12 is a precise assessment tool for severe exhibitions. The study intended to develop dengue severity score to evaluate severe manifestations amongst hospitalized patients with dengue infection.

Children and Youngsters with serologically established dengue infection admitted at Ramathibodi hospital from 2004 to 2018 and handled through an expert multidisciplinary team have been recruited. Clinical information have been retrospectively reviewed and 14 items, associated with clinical parameters and managements in the course of hospitalization, were received day by day as dengue severity score.

One hundred and ninety-one patients with a median age of 10.7 years from 2004 to 2013 had been recruited. They were categorized as dengue fever (35), Dengue hemorrhagic fever (DHF) (DHF) I (53), II (50), III (37) and IV (16). The investigation of 593 daily records revealedthat the range of daily severity score between patients with DHF grades III (10-20) and IV (31-47) were expressively higher than those of other groups (dengue fever, 5-13; DHF I, 2-10; DHF II, 6-11) with P-values of 0.0001. A total daily score of ≥12 was an assessment tool for dengue shock syndrome with sensitivity, 86% and specificity, 84%. A supplementary 51 hospitalized patients with DHF grades II, III and IV with a like ages from 2014 to 2018 were enlisted. It was found that the total of patients with severe manifestations, having daily score of ≥12, was pointedly higher than those without severe manifestations starting from Day -3 to Day +1 of illness.

Source: Pediatr Infect Dis J. 2020 Mar;39(3):184-187.

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