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WHO update on new molecular assays for diagnosis of TB and drug resistance

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eMediNexus    18 February 2021

The World Health Organization (WHO) has announced vital updates on new molecular as says in a Rapid Communication, which is expected to result in significant improvements in the diagnosis of tuberculosis (TB) and drug resistance among adults, adolescents as well as children.

A meeting of a Guideline Development Group was convened in December 2020 to update WHO policies on molecular assays employed for the diagnosis of TB and drug resistance. The evidence reviewed and presented in the Rapid Communication point to high diagnostic accuracy for 3 new technologies, including moderate complexity automated Nucleic Acid Amplification Tests (NAATs), to detect TB and resistance to rifampicin and isoniazid; low complexity automated NAATs to identify resistance to isoniazid and second-line anti-TB agents; and high complexity hybridization-based NAATs to detect resistance to pyrazinamide… (WHO, February 17, 2021)

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