The updated 2021 Kidney Disease: Improving Global Outcomes (KDIGO) clinical practice guideline for the management of blood pressure in adults with chronic kidney disease (CKD) not on dialysis advises a target systolic blood pressure of <120 mmHg, given that the measurements are standardized and that the blood pressure is measured properly.

The blood pressure target is based on evidence from the Systolic Blood Pressure Intervention Trial (SPRINT). This portrays a major update from the 2012 KDIGO guideline wherein clinicians were advised to treat to a target blood pressure of ≤130/80 mmHg for patients with albuminuria and ≤140/90 mmHg for patients without albuminuria. The new target is also lower than the target of <130/80 mmHg recommended in the 2017 American College of Cardiology/American Heart Association (ACC/AHA) guideline… (Medscape)