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COVID-19 in pregnancy tied to adverse maternal and fetal outcomes

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eMediNexus    28 March 2021

SARS-CoV-2 infection in pregnancy has been found to be associated with increased risks of preeclampsia, preterm birth and other adverse pregnancy outcomes in a meta-analysis published in the Canadian Medical Association Journal.

The meta-analysis included 42 studies involving 438,548 pregnant women. In comparison with no infection, SARS-CoV-2 infection in pregnancy was found to be linked with preeclampsia (odds ratio [OR] 1.33), preterm birth (OR 1.82) and stillbirth (OR 2.11). Additionally, having the infection in pregnancy was tied toa heightened risk of intensive care unit (ICU) admission, NICU admission and lower birth weight, when compared with pregnancy without SARS-CoV-2 infection. Severe COVID-19 during pregnancy had a strong link with preeclampsia, preterm birth, gestational diabetes, low birth weight, NICU admission, and cesarean delivery, when compared with mild infection… (DG Alerts)

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