Aim:

A study evaluated the effectiveness of neutrophil/lymphocyte ratio (NLR), in comparison with conventional inflammatory markers, to predict noninvasive mechanical ventilation (NIMV) failure in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD).

Methods: 

• It was a retrospective observational study enrolling 212 AECOPD patients who needed NIMV during hospitalization.
• The medical record was reviewed to assess the success of NIMV for each patient
• NLR was compared with traditional markers (leukocyte, C-reactive protein [CRP] and procalcitonin [PCT]) for patients in NIMV failure and NIMV success groups.
• The accuracy of these markers for predicting NIMV failure was assessed.

Results: 

Reference-

Sun W, Luo Z, Jin J, Cao Z, Ma Y. The Neutrophil/Lymphocyte Ratio Could Predict Noninvasive Mechanical Ventilation Failure in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Retrospective Observational Study. Int J Chron Obstruct Pulmon Dis. 2021;16:2267-2277.

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