Liver Update: Intestinal gluconeogenesis prevents obesity-linked liver steatosis and non-alcoholic fatty liver disease |
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Liver Update: Intestinal gluconeogenesis prevents obesity-linked liver steatosis and non-alcoholic fatty liver disease

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Hepatic steatosis with obesity may lead to non-alcoholic fatty liver disease (NAFLD) and associated complications like cirrhosis or cancer. Intestinal gluconeogenesis (IGN) can cause metabolic benefits of specific macronutrients like protein or soluble fibre, via the initiation of a gut-brain nervous signal triggering brain-dependent regulations of peripheral metabolism. A study investigated the effects of IGN on liver metabolism, independently of its initiation by the given macro...
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