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Bromhexine Hydrochloride for Moderate COVID‐19: The Mucolytic Agent May Help COVID Patients

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eMediNexus    09 December 2021

Table. Efficacy outcomes in the study

OutcomeBromhexine groupControl group
Time to fever remission (days, median (interquartile))10.5 (9.3-11)11.5 (9.5-12)
Remarkable/complete improvement in CT (%)66.733.3
Patients requiring oxygen therapy (%)16.733.3
Rate of discharge within 20 days (%)83.333.3

Reference

Li T, Sun L, Zhang W, et al. Bromhexine Hydrochloride Tablets for the Treatment of Moderate COVID-19: An Open-Label Randomized Controlled Pilot Study. Clin Transl Sci. 2020 Nov;13(6):1096-1102.

What is the message here?

Bromhexine could be potentially beneficial in patients with mild to moderate COVID-19 and large-scale clinical trials should be conducted to confirm the same.

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