According to new research, some vaccinated inflammatory bowel disease (IBD) patients appeared to get sicker during COVID-19 infections.

Out of 141 partially or fully vaccinated IBD patients who had COVID-19 infections, 8.5% required hospitalization, noted researchers in a study presented at the virtual Crohns & Colitis Congress. Although not significant, hospitalization rates appeared to be numerically higher for patients who had incomplete COVID-19 vaccinations (13.2% vs. 5.7% with complete vaccination), received non-mRNA vaccines (22.7% with adenovirus-vector vs. 16.7% with inactivated virus vs. 4.7% with mRNA vaccines), and were receiving immunomodulators (27.3%) or combination therapy (10.0%), instead of biologic monotherapy (4.2%). Among the vaccinated group, the endpoints of severe COVID-19 infection (composite of intensive care unit admission, mechanical ventilation, or death) or death alone were lower than those noted for a separate cohort of 2,317 unvaccinated individuals. The hospitalization rate following infection in the unvaccinated group was reported as 9.3%... (Medpage Today)