Reduced NREM sleep is associated with tau pathology in early Alzheimer's disease
A study of older adults reported in the journal Science Translational Medicine Jan. 9, 2019 has shown that non-rapid eye movement (non-REM) sleep slow wave activity was inversely related to Alzheimers pathology, especially tauopathy. The authors say that changes in NREM slow wave activity, especially at 1 to 2 Hz, might be able to discriminate tau pathology and cognitive impairment either before or at the earliest stages of symptomatic Alzheimers disease.
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