Post Kala-azar Dermal Leishmaniasis |
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Post Kala-azar Dermal Leishmaniasis
Dr Nilay Kanti Das, Bankura, West Bengal,  23 January 2019
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PKDL serves as reservoir of L. Donovani in the inter-epidemic period of kala-azar; thus elimination of PKDL is necessary to achieve the WHO regional target of elimination of kala-azar by 2020.Increased IL10, IgG1, IgG3, FOXP3; and decreased langerhans cells, CD86, CD28, receptor of INF gamma and TNF alpha are predictors for development of PKDL.Photosensitivity, mucosal and genital involvement, sparing of vaults of axillae and groins are key clinical features helping to differentiate from leproma...
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