EXPLORE!

Does Diabetes Mellitus Affect the Clinical Outcomes in Patients with DES?

  931 Views

Dr Ashwin Mehta, Mumbai    05 March 2019

Diabetes mellitus (DM) is known to predict angiographic restenosis and ischemia-driven target lesion revascularization (TLR) and target vessel revascularization (TVR) after PCI with bare-metal stents (BMS). Use of DES significantly reduces restenosis rates in patients with and those without DM, compared with BMS. Lesions in patients with DM are known to be longer and diffuse than in patients without DM. DM thus seems to be a risk factor for restenosis given the propensity for more complex lesions in this condition. A study assessed if baseline lesion complexity affects DES outcomes according to diabetic status. DM was shown to be a risk factor for repeat revascularization only in those patients with complex lesions. Patients with DM and noncomplex lesions had similar rates of 1-year freedom from repeat revascularization as patients without DM.

Tuxedo India study, headed by Dr. U. Kaul, interventional cardiologist from Batra Hospital, New Delhi has noted that Xience (EES) were superior to Taxus (PES) with regard to several end points, including target-vessel failure, myocardial infarction, and stent thrombosis, in diabetes patients.

The benefits of Xience (EES) vs. Taxus (PES) in the diabetic population seen at one year were maintained at two years.

To comment on this article,
create a free account.

Sign Up to instantly get access to 10000+ Articles & 1000+ Cases

Already registered?

Login Now

Most Popular Articles

News and Updates

eMediNexus provides latest updates on medical news, medical case studies from India. In-depth medical case studies and research designed for doctors and healthcare professionals.