• Turner syndrome (TS) is the commonest chromosomal abnormality in females.
• It is an important cause of short stature and primary ovarian insufficiency in females. It is never too late to diagnose TS. It is associated with a risk of atherosclerosis and congenital heart disease.
• Cardiovascular disease is the most serious health issue. Hence, active surveillance is the key. Detection at diagnosis and sequential follow-up by specialist at regular intervals are needed. Aggressive BP control is important.
• Spontaneous pregnancy is rare due to follicular depletion. Solution is in vitro fertilization (IVF) with donor oocyte. It is important to keep an eye on possible comorbidities.
• Yearly check for thyroid disease, glucose intolerance, dyslipidemia, liver abnormalities and celiac disease should be conducted.
• Screening for hearing loss is needed. Neuropsychiatric evaluation may be done, as and when needed.
• Special touch with the patient with TS is needed for long-term follow-up.

Hormone replacement therapy (HRT) is a must unless proved otherwise.