Anti-Müllerian hormone (AMH), initially considered as a male hormone, has emerged as an invaluable tool for assessment of ovarian function in childhood, adolescence and adult females. Serum AMH is an autonomous marker reflecting ‘acyclic ovarian activity’.

Advantages of AMH as an attractive diagnostic tool include: nonsignificant inter- and intra-cycle variation during the menstrual cycle; lack of modification during short-term gonadotropin-releasing hormone (GnRH) analogue administration; and age-related decline, which begins much earlier than other ovarian markers.

Strong correlation with follicle numbers, operator independency and accurate prediction of reproductive lifespan makes it a timely and reliable indicator.