Research advances on the effect of mechanical tension in post-traumatic hypertrophic scar formation |
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Research advances on the effect of mechanical tension in post-traumatic hypertrophic scar formation

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The traumatic scar has a devastating effect not only on the appearance and function of patients but also on their psychological health status and quality of life to varying degrees. Presently, researchers have confirmed that mechanical tension promotes the proliferation of inflammatory cells, fibroblasts, and other cells, as well as angiogenesis and epithelialization through a variety of mechanical conduction pathways and thus plays an important role in the formation of hypertrophic scar. 

Clinical studies have demonstrated surgical methods and adjuvant treatment to reduce the mechanical tension on the wound, which can further promote wound healing and inhibit hyperplasia of the scar. 

Source: Zhonghua Shao Shang ZaZhi. 2021 Jun 20;37(6):586-590. Chinese. doi: 10.3760/cma.j.cn501120-20200315-00167. PMID: 34167285.

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