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Metformin Journey of 6 Decades: Weed to a Wonder Drug

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Dr YP Munjal    27 November 2018

Metformin is the first-line drug for the treatment of T2DM. Metformin could be recommended as first-line treatment for patients with T2DM and HF who have preserved or moderately reduced renal function (eGFR >30 mL/min). Metformin therapy is associated with a reduction in newly incident HF and in HF mortality. Metformin’s approved, as well as the off-label indications, include prediabetes, T2DM, T1DM, cancer prevention, anti-aging, Metabolic syndrome, PCOS, etc. The list of cancers against which metformin is protective is growing rapidly which includes cancers of the breast, endometrium, prostate, pancreas, liver, lung, colon, etc. Those seeking to gain the longevity benefits associated with reduced glucose and insulin levels can benefit tremendously from metformin’s anti-aging property.

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