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Indian contribution to GI motility and functional GI Disease Research

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Dr Uday C Ghoshal, Lucknow    05 December 2018

  • Gut-brain interaction has been suggested as a process underlying the occurrence of functional gastrointestinal disorders.
  • Rome IV: Multi-dimensional clinical profile (MDCP)
  1. MDCP profile: Categorical diagnosis (symptom-based criteria); Clinical modifier (IBS-C, D, M, post-infectious, FODMAP sensitive); Impact (mild, moderate, severe); Psychosocial modifier; Physiological dysfunction and biomarker
  2. Biological factors: IBS-C: Fecal evacuation disorder; Slow transit. IBS-D: Lactose or fructose malabsorption; Bile acid malabsorption; Non-celiac wheat sensitivity; Small intestinal bacterial overgrowth; Post-infection.

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