Register
Antibiotics after Assisted Vaginal Delivery Reduce Infections |
Journal Updates
eMediNexus Coverage from: 
Antibiotics after Assisted Vaginal Delivery Reduce Infections

1 Read Comments                

A blinded, randomized, placebo-controlled trial, published online May 13 in The Lancet, suggests that prophylactic antibiotic administration within 6 hours of assisted vaginal delivery can considerably reduce infection rates in the 6-week post-delivery period.

Marian Knight, MBChB, DPhil, FFPH, FRCPE, from the University of Oxford, United Kingdom, and colleagues, state, "From our results, a high proportion of women — almost one in five —experience an infective complication and this can be reduced by almost half,"

Investigators noted that only 11% (180/1619) of women in the antibiotic group developed an infection compared with 19% (306/1606) in the placebo group (risk ratio 0.58; 95% confidence interval, 0.49 – 0.69). Additionally, significantly less women in the antibiotic group reported perineal pain, need for perineal care, or wound breakdown in comparison with women in the placebo group.

To comment on this article,
create a free account.
Sign Up to instantly read 30000+ free Articles & 1000+ Case Studies
Create Account

Already registered?

Login Now