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Molecule Updates

Effects of dipeptidyl peptidase-4 inhibitors on bone fractur
eMediNexus, 18 January 2018
#Diabetes and Endocrinology #Internal Medicine #Orthopedics

A new study published in PLoS One aimed to evaluate the effects of dipeptidyl peptidase-4 inhibitors (DPP-4is) on bone fracture in type-2 diabetes mellitus (T2DM) patients. This was a systematic review and ne ...MORE

568 Views
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Can canagliflozin decrease epicardial fat in patients with t
eMediNexus, 17 January 2018
#Cardiology

A study was performed to determine whether canagliflozin can reduce the thickness of epicardial adipose tissue, that is associated with insulin resistance and is a risk factor for coronary artery disease. The results ...MORE

597 Views
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Assessing the impact of canagliflozin therapy on HbA1c, body
eMediNexus, 17 January 2018
#Cardiology #Diabetes and Endocrinology

A study published in the Current Medical Research and Opinion journal assessed the achievement of composite endpoints of glycated hemoglobin (HbA1c), body weight (BW), and systolic blood pressure (BP) targets ...MORE

631 Views
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Azilsartan associated with increased circulating angiotensin
eMediNexus, 15 January 2018
#Nephrology

Activation of angiotensin (ANG) II type 1 receptors (AT1R) tends to stimulate vasoconstriction, inflammation, and renal dysfunction. A study assessed the ability of azilsartan (AZL) to modulate levels of plasma ANG-(1 ...MORE

504 Views
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Effect of cilnidipine on left ventricular diastolic function
eMediNexus, 15 January 2018
#Nephrology

A study, published in the Japanese Circulation Journal, evaluated the mechanisms of improvement in left ventricular (LV) diastolic function in hypertensive patients treated with cilnidipine using pulsed Doppl ...MORE

457 Views
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A diagnostic approach to pruritus.
eMediNexus, 12 January 2018
#Dermatology #Internal Medicine

An article published in American Family Physician reported that pruritus can be a symptom of a distinct dermatologic condition or of an occult underlying systemic disease. It was stated that of the patients r ...MORE

526 Views
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