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Live-Attenuated RSV Vaccine with Deletion of RNA Synthesis Regulatory Protein M2-2.
eMediNexus,  27 June 2019
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#Allergy and Immunology #Infectious Diseases #Internal Medicine

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Respiratory syncytial virus (RSV) causes about 33 million episodes of lower respiratory illness (LRIs) and up to 118,200 deaths annually. The goal of a new study published in Open Forum Infectious Diseases was to evaluate LIDcp∆M2-2, a version of LID∆M2-2 (a candidate vaccine with M2-2 deletion), that was further attenuated by an additional set of 5 well-characterized attenuating mutations derived from cold-passaged (cp) RSV [12, 13] in RSV-seronegative children aged 6–24 mont
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