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Cognitive behavioral therapy (CBT) for major depression appears to be slightly more cost effective than treatment with second-generation antidepressants (SGAs) in the long run and shows equivalent, or even superior, efficacy.
Results from a meta-analysis, as well as additional clinical and economic data, show that SGAs for major depressive disorder (MDD) were 70% more likely to be cost effective at 1 year, while CBT was 75% more likely to be cost effective at 5 years with a suggested efficacy advantage. The study was published online October 28 in the Annals of Internal Medicine.