Tranexamic acid displays high potential in the treatment of obstetric hemorrhage


eMediNexus    24 November 2017

Obstetric hemorrhage an important cause of maternal mortality across the world could be attributed to increased fibrinolytic activity secondary to release and activation of endothelial tissue plasminogen activator. The researchers thus performed a study to assess the effect of tranexamic acid an anti fibrinolytic agent in this set of individuals. The findings of a large randomized controlled trial demonstrated that tranexamic acid administered to hemorrhaging women within 3 hours after delivery was associated with reduced risk of death resulting from bleeding. Moreover there was no increase in thromboembolic complications. Therefore it can be suggested that tranexamic acid seems to be an effective agent with a favorable safety profile in the treatment of obstetric hemorrhage.

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