Impact of constipation treatment in overlap of GERD and functional constipation in children


eMediNexus    25 November 2017

This study was conducted to explore the frequency of gastroesophageal reflux disease GERD in children with functional constipation FC . The study also evaluated the improvement level in reflux symptoms by measuring the acid reflux in these patients after they were given FC treatment. Ninety four children with constipation were prospectively evaluated. 24 hour pH meter monitoring was done in 55 patients with GERD symptoms. Patients with abnormal acid reflux were administered conventional therapy for FC. These cases were re evaluated for GERD symptoms and weekly defecation frequency and 24 h pH meter monitoring was performed at the end of a 3 month period. Twenty three of the 55 cases had an abnormal level of acid reflux. Following constipation treatment a significant improvement was achieved in the acid reflux index and GERD symptoms whereas the weekly defecation frequency increased. Treatment of constipation can thus improve the reflux symptoms and abnormal acid reflux in these cases. Physicians should consider the co occurrence of these two problems for better disease management.5 References 5. Masallah B Yeliz CA Miray K et al. The overlap of gastroesophageal reflux disease and functional constipation in children the efficacy of constipation treatment. Eur J Gastroenterol Hepatol. 2017 29 11 1264 8. doi 10.1097 MEG.0000000000000979.

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