Zinc Update:Effect of zinc supplementation on psychological and physical symptoms in young females with premenstrual syndrome |
Journal Updates
eMediNexus Coverage from: 
Zinc Update:Effect of zinc supplementation on psychological and physical symptoms in young females with premenstrual syndrome
eMediNexus,  21 November 2020
Coronavirus Live Count Map India

remove_red_eye 1220 Views
#Allergy and Immunology

0 Read Comments                

 

Zinc is an essential nutrient that is known to have several beneficial effects that includes antioxidant, anti-inflammatory and anti-depressant actions. Evidence on the effects of supplementation of zinc on biomarkers of oxidative stress, inflammation and antidepressant-like effects in young women with premenstrual syndrome (PMS) are limited. A randomized, placebo-controlled and double-blind trial was conducted. Almost sixty women, aged 18-30 years with PMS were diagnosed as per the 30-item questionnaire and were randomly allotted to receive either 30-mg zinc gluconate (group 1; n = 30) and placebo (group 2; n = 30) for almost 12 weeks. Premenstrual syndrome symptoms, high sensitivity reactive protein, total antioxidant capacity, and brain-derived neurotrophic factor were evaluated at study baseline and then at 12-week intervention.

PMS physical symptoms and psychological symptoms significantly reduced in the zinc group as compared to placebo group after 12 weeks of intervention. A significant increase in brain-derived neurotrophic factor and total antioxidant capacity was observed after 12 weeks of intervention with zinc as compared to placebo.

Thus, the study concluded that zinc supplementation for 12 weeks in women with premenstrual syndrome revealed beneficial effects on physical and psychological symptoms of PMS, total antioxidant capacity along with brain-derived neurotrophic factor.

Source: Biol Trace Elem Res. 2020 Mar;194(1):89-95.

To comment on this article,
create a free account.
Sign Up to instantly read 30000+ free Articles & 1000+ Case Studies
Create Account

Already registered?

Login Now