Vitamin E, as an essential fat-soluble antioxidant, has been used for over 50 years indermatology. It is also an essential ingredient in many cosmetic products protecting the sin from many deleterious solar radiation effects by acting as a free-radical scavenger. Some of the essential usages of vitamin E in dermatology practice include:

Yellow nail syndrome: Vitamin E is one of the treatment modalities for yellow nail syndrome in a dosage of 1000 IU once a day for six months

Subcorneal pustular dermatoses: Vitamin E 100 IU/day, gradually increasing to 400 IU/day for four weeks is one of the therapies for subcorneal pustular dermatoses, especially those showing unsatisfactory response to conventional medications.

Atopic dermatitis: in a single-blind, placebo-controlled study, oral vitamin E (400 IU/day) for eight months led to an improvement and remission of atopic dermatitis and a 62% reduction in serum IgE correlation between vitamin E intake, IgE levels, and the clinical manifestations of atopy indicate that vitamin E could be a therapeutic tool for atopic dermatitis.

Reference: Keen MA, Hassan I. Vitamin E in dermatology. Indian Dermatol online J. 2016; 7 (4): 3110315.