Women are at risk of acute and chronic liver diseases and the diseases affecting pregnant women with adverse effects on maternal, fetal, or neonatal outcomes are of utmost importance. Among these diseases, acute viral hepatitis is a crucial cause of liver disease in pregnant women, and hepatitis E infection is correlated with significant mortality. It has been observed that there is rising trend among women with chronic liver diseases caused by viral hepatitis, alcoholic liver disease and nonalcoholic fatty liver disease, autoimmune liver diseases, and genetic liver diseases. 

The presence of chronic liver diseases or cirrhosis in pregnant or non-pregnant women varies in term of gynecologic care, including contraception, pregnancy planning, cervical cancer screening, human papillomavirus vaccination, and postmenopausal hormone therapy. Gynecologic care is required to cater immunosuppressed status in women who had liver and other solid organ transplantation. An association between obstetrician-gynecologists and hepatologists is important to offer appropriate care to women with acute or chronic liver diseases. Thus, early and prompt referral for assessment for liver transplantation is essential for all women with acute liver failure.

Source: Clinical Updates in Womens Health Care Summary: Liver Disease: Reproductive Considerations. Obstet Gynecol. 2017 Jan;129(1):236.