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South African variant could diminish vaccine protection, says Pfizer

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eMediNexus    18 February 2021

The South African variant of the coronavirus may cause a two-thirds reduction in the antibody protection provided by the Pfizer/BioNTech vaccine, suggests a laboratory investigation. It is still not known whether the vaccine will be effective against the mutation, stated the companies.

According to the study, the vaccine could neutralize the virus and evidence is not yet available from trials in people to suggest that the variant alters the protection extended by the vaccine.

Investigators studied an engineered virus and the blood obtained from individuals who had received the vaccine. There was a decline in the level of neutralizing antibodies by two-thirds compared to its effect on the most common version of the coronavirus in U.S. trials. The study is published in the New England Journal of Medicine… (Reuters, February 18, 2021)

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