Asymptomatic Bacteriuria and Urinary Tract Infection in Pregnancy


Dr Divya Bajpai, Mumbai    11 January 2018

  1. Suppressive therapy throughout the pregnancy is warranted for persistent ABU. Early empirical treatment in acute cystitis awaiting culture results -better outcome. Acute pyelonephritis poses risk of maternal and fetal complication in more than 20% of cases. Early parenteral broad-spectrum antibiotics are warranted, can be switched to oral tailored to susceptibility profile once patient is afebrile. Penicillins, cephalosporins, aztreonam and fosfomycin are the safest alternatives. Nitrofurantoin and TMP-SMX to be avoided in 1st trimester and at term.

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