• Rhabdomyolysis refers to the breakdown of skeletal muscle and is marked by the release of its cellular content into the circulation.
• The most common acquired causes of rhabdomyolysis include substance abuse, medication, trauma, and epileptic seizures, while the less common causes include infections, metabolic disorders, local and/or general muscle ischemia, prolonged immobility, exercise, and excessive heat.
• Uysal and colleagues published a case report in the American Journal of Tropical Medicine and Hygiene of a patient who initially presented with rhabdomyolysis and was later diagnosed with COVID-19.

• In rare COVID-19 cases, patients may not have the classic symptoms. 
• Clinicians should therefore be aware of the atypical presentation of COVID-19 infection, especially in patients with contact history.
• This patient did not have any symptoms and contact history of COVID-19. He only complained of severe muscle aches. Following examination, rhabdomyolysis was diagnosed. However, there was no history of the comorbid disease or drug use that could cause rhabdomyolysis.
• In this patient, muscle pain and raised enzyme due to muscle destruction suggested that rhabdomyolysis occurred as a result of SARS-CoV-2 infection.

Reference

Uysal BB, Ikitimur H, Yavuzer S, et al. Case Report: A COVID-19 Patient Presenting with Mild Rhabdomyolysis. Am J Trop Med Hyg. 2020 Aug; 103(2): 847–850.