A prospective, multicenter observational study that analyzed whether serum albumin concentration upon hospital arrival had prognostic indications on out-of-hospital cardiac arrest demonstrated that higher serum albumin concentration was remarkably and independently linked with favorable neurological outcome in a dose-dependent manner. Based on the serum albumin concentration upon hospital arrival, patients were allocated into 4 quartiles: Q1 (< 2.7 g/dl), Q2 (2.7-3.1 g/dl), Q3 (3.1-3.6 g/dl), and Q4 (≥ 3.6 g/dl). The results published in the American Journal of Cardiology showed that highest proportion of favorable neurological outcome was 33.5% in the Q4 group, followed by 13.2%, 5%, and 3.5% in the Q3, Q2, and Q1 groups, respectively.