A study published in the American Journal of Cardiology evaluated the relation between global cardiac calcification estimated by a previously validated echocardiographic calcium score (eCS) with the severity of mitral stenosis (MS) and coronary artery disease (CAD) in patients with a clinical diagnosis of severe calcific aortic stenosis (AS). The results showed that global cardiac calcification is associated with MS and CAD in patients with severe calcific AS. Moreover, eCS displayed the potential for predicting the presence of MS. Higher mean eCS was seen in patients with more severe MS. In addition, higher eCS was also inversely linked with mitral valve area and positively associated with mitral valve mean pressure gradient and mitral valve peak flow velocity. The investigators suggested that a simple eCS may help in stratifying risk in patients with severe calcific aortic valve stenosis.