A new finding linking insulin resistance and acne manifestation in post-adolescent males has been found. This could aid in early adulthood diagnosis of pre-diabetes and risk of future diabetes. Similar evidence linking polycystic ovary syndrome with hirsutism and skin pigmentation disorders acanthosis nigricans (particularly on the axillae) has been found in females. Presence of cutaneous manifestations of common endocrine disorders should be noted and lead physicians to promptly explore patients for metabolic abnormalities. These patients would require immediate follow up with an diabetes, endocrinology, and metabolism specialist. Early diagnosis and prevention of metabolic disorders is critical in India, the diabetes capital of the world, also hosting a significant portion of the global polycystic ovary disorder population; all physicians should note these findings, both from studies published online on December 23rd in JAMA Dermatology, by Dr. Mohit Nagpal, MD, Post Graduate Institute of Medical Education and Research (PGIMER) Chandigarh, and Dr. Timothy Schmidt, MD, PhD, University of California, San Francisco (UCSF), respectively. Further links between dermatological markers and hormonal imbalance are likely to be found in the near future.