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ASCO clinical practice guidelines for HER2-positive breast cancer |
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ASCO clinical practice guidelines for HER2-positive breast cancer

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The American Society of Clinical Oncology (ASCO) has updated its clinical practice guidelines on systemic therapy for patients with human epidermal growth factor receptor 2 (HER2)–positive advanced breast cancer published online June 25, 2015 in the Journal of Clinical Oncology. As per the guideline, HER2-targeted therapy is recommended for patients with HER2-positive advanced breast cancer, except for patients with clinical congestive heart failure or significantly compromised left ventricular ejection fraction, who should be evaluated on a case-by-case basis.

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