Pregnancy outcomes associated with extended use of levonorgestrel-releasing intrauterine system.


eMediNexus    26 October 2017

A new study published in Contraception assessed the contraceptive performance of the 52 mg 20 956 g day levonorgestrel releasing intrauterine system among women who maintain the same device without changes after 60 months. This review identified charts of 766 women who continue the same LNG IUS for contraception beyond 60 months. The findings revealed that the mean age at LNG IUS placement was 15 to 44 years with a median of 32 years. The median length of the LNG IUS use was 73 months after placement ranging from 61 to 184 months. No incidence of pregnancy was reported and the main reasons for discontinuation of the device were expiration of approved effective lifespan menopause and planning of pregnancy. The cumulative women years W Y of exposure were 967 and 1485 up to seven and 15 years respectively. While the main bleeding pattern reported by the women was amenorrhea. The results were summarized as 52 mg 20 956 g day LNG IUD showed continued contraceptive efficacy beyond 5 years of us with no pregnancies detected over 967 and 1485W Y up to seven and 15 years after placement. Thus it was concluded that the 52 mg 20 956 g day LNG IUD presented a very high contraceptive efficacy beyond the first five years of lifetime labelled the findings indicated efficacy as long as 15 years. It was stated that healthcare professionals policy makers and stakeholders could utilize this information in decision making for the maintenance of the same device up to at least seven years. Moreover amenorrhea could be a good indicator of contraceptive effect.

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