Poor sleep quality, particularly from frequent nocturnal urination is strongly associated with nighttime blood pressure (BP) abnormalities, as per results from the Nagahama study published in the Journal of Hypertension (J Hypertens. 2018 Nov;36(11):2185-92). Systolic BP decreased 8.5% on average. The frequency of urination showed strong and independent association, with smaller nocturnal BP drop in patients with frequent nocturnal urination. Other associations with BP became nonsignificant after adjustment, including the sleep fragmentation index and 3% oxygen desaturation index. Abnormalities in circadian BP variation, particularly increase in nocturnal BP, have been reported to be risk factors for cardiovascular disease.