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FDA says certain antibiotics could rupture main artery

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Dr KK Aggarwal    03 January 2019

As per new US FDA warning fluoroquinolones antibiotics "can increase the occurrence of rare but serious events of ruptures or tears in the main artery of the body," the aorta and lead to dangerous bleeding or even death.

The FDA is requiring drug makers to add a new warning to the packaging, saying "fluoroquinolones should not be used in patients at increased risk unless there are no other treatment options available." The FDA says those patients are ones with "a history of blockages or aneurysms" of blood vessels, high blood pressure, certain genetic disorders and the elderly. 

This is the latest warning about fluoroquinolones.

In 2015, some patients and doctors blamed the antibiotics for devastating side effects, including ALS, Alzheimers, Parkinsons and even death.

In 2016, the FDA required drug makers to include warnings the drugs could have disabling effects on tendons, muscles, joints and nerves. Later that year, the FDA added more warnings about the risks of mental health side effects and serious blood sugar disturbances.

 

Dr KK Aggarwal

Padma Shri Awardee

President Elect Confederation of Medical Associations in Asia and Oceania   (CMAAO)

Group Editor-in-Chief IJCP Publications

President Heart Care Foundation of India

Past National President IMA

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