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Neurofilament light chain may be a potential biomarker for predicting progression of Alzheimer's disease
eMediNexus,  22 January 2019
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#Neurology #Pathology and Lab Medicine #Psychiatry

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Serum NfL predicts disease progression and brain neurodegeneration at the early presymptomatic stages of familial Alzheimer’s disease, as per a study reported in Nature Medicine. Serum neurofilament light chain (NfL) levels correlated with NfL levels in the cerebrospinal fluid (CSF) and were elevated at pre-symptomatic stages of familial Alzheimers disease There were noticeable changes in blood up to 16 years before the calculated onset of dementia symptoms.
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