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At what cut-off should subclinical hypothyroidism be mandatorily treated?

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Dr Parimal Tayde, Nagpur    27 November 2019

Guidelines generally recommend thyroid hormones for adults with thyroid-stimulating hormone (TSH) levels above 10 mIU/L. For those with lower TSH levels, most guidelines recommend treatment only when people are younger, symptomatic or have other indications for prescribing (such as cardiovascular disease or antibodies to thyroid peroxidase).

Please opine on the management of hypothyroidism in pregnancy.

Hypothyroidism is widely prevalent in pregnant women and the rate of detection, especially in a developing country like India, has not kept pace with the magnitude of the problem. Since hypothyroidism is easily treated, timely detection and treatment of the disorder could reduce the burden of adverse fetal and maternal outcomes, which are very commonly encountered.

What are the complications of subclinical hyperthyroidism? How is it managed?

Treatment of subclinical hyperthyroidism is mandatory in older patients (>65 years) or in the presence of comorbidities such as osteoporosis and atrial fibrillation.

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