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Safe and Smart Use of Modern Sulfonylureas: The Compelling Benefits

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Dr SR Aravind, Bengaluru    26 November 2018

  1. Sulfonylureas (SUs) are important components in the treatment of T2DM.
  2. Treatment with SUs results in maximum reduction of HbA1c.
  3. Modern SUs like glimepiride have a durable action and β-cell exhaustion with SUs is a myth.
  4. Modern SUs cause negligible weight gain and lesser hypoglycemia; glimepiride causes the least.
  5. Due to their well-established efficacy and safety profile, modern SUs are the most frequently used with metformin.
  6. Modern SUs are not associated with the risk of CV mortality.
  7. SUs are cost-effective.

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