Patients have become more aware now. They consult their doctors as soon as they sense that something is wrong. As a result, patients are being diagnosed early. ...MORE
Self-monitoring of blood glucose (SMBG) has become an integral part of diabetes care. It helps in formulating new drug regimens and optimizing the existing regi ...MORE
Many people with diabetes have depression that may manifest as poor adherence to diet, medication and SMBG. This can have an adverse impact on the overall manag ...MORE
There are limited therapeutic options to treat obesity. Higher doses of metformin and drugs like SGLT-2 inhibitors can reduce weight in patients with diabetes. ...MORE
Separation of other forms of young-onset diabetes from inherited forms should be primarily sought.Delineating a Pedigree chart with an insight into other syndro ...MORE
Replacement is needed below a vitamin D level of 30 ng/mL.Is daily vitamin D better than monthly?For correction of deficiency, either weekly or daily preparatio ...MORE
Primary adrenal insufficiency (AI) is more common than secondary (pituitary) AI. Commonest cause of AI in India still would be tuberculosis; however, autoimmune ...MORE
An HbA1c level of <7% is recommended by most guidelines. However, it must be understood that treatment needs to be individualized according to each patient a ...MORE
Guidelines generally recommend thyroid hormones for adults with thyroid-stimulating hormone (TSH) levels above 10 mIU/L. For those with lower TSH levels, most g ...MORE
I (the doctor) have done nothing that any reasonable prudent doctor would not have done (act of commission) nor I have refrained from doing anything, which a re ...MORE
The testosterone therapy preparations that are commonly available include testosterone injections (enanthate, cypionate, undecanoate), patches, gels and tablets ...MORE
The best treatment strategy is surgical excision of the tumor. Residual disease can be managed by medical or radiotherapy.How do you manage prolactinoma in preg ...MORE
Diabetology needs an adaptation process to incorporate new tools for diabetes management. Technology and particularly sensors and computer applications have bec ...MORE
Turner syndrome (TS) is the commonest chromosomal abnormality in females.It is an important cause of short stature and primary ovarian insufficiency in females. ...MORE
Gluconeogenic and glycogenolytic enzymes are immature in utero.The maximum risk of hypoglycemia is in the first 24 hours of life and definitely not after 72 hou ...MORE
Fracture risk and fracture-related complications and costs are higher in type 2 diabetes mellitus and chronic kidney disease (CKD) patients.DXA T score does cla ...MORE
Universal newborn screening (NBS) for congenital hypothyroidism (CH) is the need of the hour in India. Recall for rescreening and subsequent venous confirmatory ...MORE
Dipeptidyl peptidase 4 (DPP-4) inhibitors play a role in simplifying diabetes management and are featured in international guidelines.DPP-4 inhibitors are assoc ...MORE
The prevalence rates of diabetes are rising rapidly both in urban and rural India. Education is the cornerstone of diabetes care (WHO). Indian Diabetes Preventi ...MORE
Law and medicine are two different sciences. Medicine is therapy/indication specific.Law is specialty neutral. It has nothing to say on the science of medicine/ ...MORE
Problems of basic science research – A clinician has no formal training; He/she has no set up; He/she becomes sample provider; He/she has insight into mea ...MORE
What is your Advice to Upcoming Endocrinologists and Diabetologists?I would advice them to do more research and collate the data. It is important to talk about ...MORE
Diagnosis of Cushing’s syndrome is enigmatic.Clinical, biochemical and radiological features may not go hand-in-hand.0800 h cortisol is not employed for e ...MORE
Peroxisome proliferator-activated receptor (PPAR) agonists work as integrators of inflammatory and metabolic signaling networks; work as lipid sensors; repress ...MORE
Biological crosstalk – Components of one signal transduction pathway affect another in a number of ways, most common form being crosstalk between proteins ...MORE
High resolution ultrasound can detect thyroid nodules in 19-68% individuals. Approximately 1 in 2 people may have incidental thyroid nodules.The frequency is hi ...MORE
Morbidity and increased mortality in patients with adrenal insufficiency is unacceptable. Management of adrenal crisis is currently inadequate.Morbidity is rela ...MORE
11-oxygenated 19-carbon (11oxC19) steroids are elevated in both men and women with classic 21-hydroxylase deficiency (21OHD). 11oxC19 steroids are specific biom ...MORE
Anti-Müllerian hormone (AMH), initially considered as a male hormone, has emerged as an invaluable tool for assessment of ovarian function in childhood, ad ...MORE
Androgen deficiency in aging male (ADAM) is functional hypogonadism and is a diagnosis of exclusion.Sexual symptoms (erectile dysfunction and reduced sexual tho ...MORE
Hyperthyroidism relapses in the majority of patients with Graves’ disease treated with antithyroid drug (ATD).Among different clinical and laboratory feat ...MORE
Triad of modalities in preventing type 2 diabetes – Diet, exercise and medication.Lifestyle intervention can prevent type 2 diabetes onset. Several random ...MORE
Obesity in men and women is associated with impaired reproductive function.Preconceptional counseling for obese couples should address the reproductive and mate ...MORE
Stem cell therapies for type 1 diabetes are novel.The use of stem cells in the generation of a renewable source of b-cells remains a promising reality.A meta-an ...MORE
Thyroid storm is an important endocrine emergency. Suspect the condition in any severely ill patient with tachycardia, high fever and a thyroid swelling. Early ...MORE
This is an important differential diagnosis for adrenocorticotropic hormone (ACTH)-dependent Cushing’s syndrome. It has a more rapid and fulminant onset w ...MORE
The complications which occurred in this case are well-described in literature (quote a reference) and cannot amount to negligence. Whatever happened during tre ...MORE
Adrenal venous sampling (AVS) is the gold standard for primary aldosteronism (PA).Biochemical and radiographic tests do not reliably distinguish aldosterone-pro ...MORE
The burden of type 2 diabetes mellitus continues to rise.The way our body handles meal-related surges in lipids and the associated postprandial triglyceride dys ...MORE
Pregnancy and lactation are physiological processes that have significant implications for calcium and vitamin D metabolism.The deficiency of calcium and vitami ...MORE
Country-wide studies have reported vitamin D deficiency in as high as 70-100% of ostensibly healthy individuals. There is a high prevalence of vitamin D deficie ...MORE
Better survival among adolescents and young adults with cancer means that fertility issues become important among survivors.Current recommendations from America ...MORE
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