Morning Medtalks with Dr KK

1. Overweight and heart burn: Being overweight or obese increases the odds of having GERD and experiencing heartburn.
2. Eating larger meals distends the stomach, pushes the contents up toward the esophagus and loosens the LES.
3. NIH: Light physical activity such as gardening, strolling through a park, and folding clothes might be enough to significantly lower the risk of cardiovascular disease among women 63 and older. This reduces the risk of cardiovascular disease events such as stroke or heart failure by up to 22 percent, and the risk of heart attack or coronary death, by as much as 42 percent. [JAMA NETWORK OPEN.]
4. Catheter ablation, appears no more effective than drug therapies in preventing strokes, deaths, and other complications in patients with atrial fibrillation. However, patients who get the procedure experience much greater symptom relief and long-term improvements in the quality of life, including fewer recurrences of the condition and fewer hospitalizations, than those who get only drugs. The findings are from two new studies published in the March 15 issue of the Journal of the American Medical Association.
5. Frequent changes to health care environments and protocol have contributed to an increased rate of burnout among physicians that has escalated into a public health crisis a recent report from the Harvard Global Health Institute concludes.
6. 2018 Survey of America’s Physicians Practice Patterns and Perspectives, found that 78 percent of respondents experienced feelings of professional burnout, a 4 percent increase from the results of a 2016 survey conducted by the Physicians Foundation.
7. Drugs typically contain the actual drug, or active pharmaceutical ingredient (API), and inactive ingredients (excipients). Inactive ingredients "are not intended or expected to have a direct biological or therapeutic effect but instead are added to alter the physical properties of an oral solid dosage form (tablet or capsule) to facilitate absorption; to improve stability, taste, and appearance; or to render the therapeutic tamper resistant. Increasing numbers of clinical reports describe allergic reactions to excipients such as lactose and chemical dyes, write Reker and colleagues in March 13 in Science Translational Medicine.

The researchers conducted a comprehensive analysis of 18 of the most commonly prescribed active ingredients (54 unique medications).

Of 38 commonly used excipients that are known to cause allergic reactions, lactose was used in 44.82% of all solid oral dosage forms in the databases searched, followed by corn starch (36.54%), polyethylene glycol (36.03%), povidone (35.8%), and carboxymethylcellulose (21.38%). Other oral medications include peanut oil, wheat starch, artificial dyes, and certain sweeteners.

For most medications, the amount of inactive ingredients accounted for half of the pill and for some that amount reached 99%.

Dated: 16th March, 2019

Current Temperature Status and Warning for next 24 hours.

Heat Wave and Temperature Observed Yesterday (Past 24 hours from 0830 hrs IST of 15 th March to 0830 hrs IST of 16 th March, 2019)

Heat Wave:

.Yesterday, No heat wave conditions were observed.

Temperatures Recorded at 1730 Hours IST of 15 th March, 2019:

Maximum Temperature

• Temperature’s more than 40.0°C was recorded at isolated places over Rayalaseema. (Annexure-1).
• Maximum temperatures were appreciably above normal (3.1°C to 5.0°C) at a few places over Rayalaseema, Assam & Meghalaya and Sub-Himalayan West Bengal& Sikkim; above normal (1.6°C to 3.0°C) at most places over Coastal Andhra Pradesh and Telangana; at many places over Chhattisgarh and Nagaland, Manipur, Mizoram & Tripura; at a few places over Lakshadweep, Kerala, Tamilnadu & Puducherry, South Interior Karnataka, Vidarbha, Madhya Maharashtra, Konkan & Goa and Saurashtra & Kutch and at isolated places over Odisha, Marathawada and Jammu & Kashmir. They were appreciably below normal (-3.1°C to -5.0°C) at most places over East Rajasthan; at many places over Punjab, west Rajasthan, Haryana, Chandigarh & Delhi; at a few places over Andaman & Nicobar Islands and Madhya Pradesh; below normal (-1.6°C to - 3.0°C) at most places over Gujarat region and West Uttar Pradesh and at isolated places over Himachal Pradesh, Uttarakhand, Bihar, Jharkhand and East Uttar Pradesh and near normal over rest parts of the country. (Annexure-2).
• Yesterday, The highest maximum temperature of 40.5°C was recorded at Anantpur (Rayalaseema) over the country.

Heat Wave Warnings for Next 24 hours(From 0830 hrs IST of 15 th to 0830 hrs IST of 16 th March 2019):