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A new study finds that people who have movement problems, symptoms that cannot be explained by an underlying disease, may have chemical changes in specific areas of the brain. The study is published in the June 5, 2019, online issue of Neurology. These symptoms, which include tremors, muscle contractions or problems with walking, are called functional or psychogenic motor symptoms.
The people with functional motor symptoms had increased levels of glutamate and glutamine in the limbic areas of the brain, with levels approximately four times higher than in the healthy people. Glutamate and glutamine were however normal outside the limbic areas, thus demonstrating that the finding is specific for these regions.