A Crohns disease exclusion diet (CDED) plus partial enteral nutrition (PEN) yielded sustained remission in a randomized controlled study of children with mild to moderate Crohns, according to Israeli and Canadian researchers.

The diet was also better tolerated than exclusive enteral nutrition (EEN) and inflammation markers were lower in those on CDED/PEN.

At week 6, a total of 30 of 40 children (75%) given CDED plus PEN were in corticosteroid-free remission versus 20 of 34 children (59%) given EEN (P=0.38), reported Johan Van Limbergen, MD, PhD, of Dalhousie University in Halifax, Nova Scotia, and colleagues in Gastroenterology.