Left atrial function after epicardial pulmonary vein isolation in patients with atrial fibrillation.


eMediNexus    17 November 2017

The aim of a new study published in the Journal of Interventional Cardiac Electrophysiology was to evaluate if epicardial pulmonary vein isolation combined with ganglionated plexi ablation affects the size and mechanical function of the left atrium and whether the effects are dependent on the extensiveness of the ablation applications. In this study 42 patients underwent an echocardiographic examination before and 6 months after a minimal invasive epicardial pulmonary vein isolation procedure for the assessment of the effects on left atrial size and function. It was observed that left atrial size and function at the 6 month follow up had not changed significantly from those at baseline as indicated by left atrial maximal area minimal area fractional area change and E A ratio. Hence it was concluded that radiofrequency ablation for epicardial pulmonary vein isolation combined with ganglionated plexi ablation has no major effects on atrial function or size. It was stated that a preserved atrial function for those maintaining sinus rhythm may have important implications for thromboembolic risk after surgery however confirmation in larger trials is warranted.

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