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#Allergy and Immunology
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A new article published in Current Opinion in Immunology discussed that the exposure to certain environments, such as farms, has the potential to protect from the development of allergies in later life. This protection is achieved when repeated exposures to the farming environment occur early in life, but persists when children spend sufficient amount of time in contact with livestock and hay and drink unpasteurized milk. The authors reported that the microbe composition in the farm is one of the factors that influence the protective capacity of the farm against allergy development. Protective microbes release various metabolites and cell wall components that change farmers home dust composition, unlike that in urbanized home dust. Furthermore, these microbes can colonize various barrier sites, for instance, skin, lung and intestine, in exposed children, leading to persistent changes in the way their immune system and barrier cells respond to various environmental allergens.